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KMID : 0613820020120050549
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Journal of Life Science
2002 Volume.12 No. 5 p.549 ~ p.554
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Taraxacum mongolieum Hand-Mass Aqua-acupuncture Solution as the Blocking Agent of Carcinogenesis
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Abstract
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Taraxacum mongolieum Hand-Mass aqua-acupuncture solution (TMAS) was prepared and investigated for the effect on initiation of carcinogenesis. The following effects as a blocking agent were measured. : (a) Induction of quinone reductase, (b) Induction of glutathione S-transferase activity (c) Increase of reduced glutathione. TMAS was potent inducer of quinone reductase in Hepa 1c1c7 murine hepatoma cells. Glutathione S-transferase activity was increased with TMAS. In addition glutathione levels were increased about 1.6-fold with TMAS in cultured murine hepatoma Hepa 1c1c7 cells.
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